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The Entourage Effect

The Entourage Effect

The entourage effect refers to the different compounds in cannabis that work synergistically to create uniquely beneficial effects. By taking the cannabis compounds together rather than alone, there’s an increased likelihood that the product will produce benefits.
The term refers to the herbal remedies that contain different compounds that work together to produce a particular impact on a person’s well-being, from easing anxiety to decreasing inflammation.

There are hundreds if not thousands of compounds in the cannabis plant. Of these, three main groups of compounds contribute to the entourage effect. These are:

1. Phytocannabinoids (plant cannabinoids) — the “feel” or “bodily effect”
compounds. Cannabis plants contain more than 120 different phytocannabinoids.These phytocannabinoids act on your endocannabinoid system, which works to keep your body in homeostasis, or balance.

2. Terpenes/terpenoids — the aromatic compounds.

Terpenes are found in the form of aromatic compounds, the compounds responsible for the distinctive scents of the plant. For example, limonene is a terpene that can be found in lemon peels, while eucalyptol can be found in eucalyptus.

3. Flavonoids — the flavor compounds.

 Flavonoids are a broad category of chemicals found in all manner of plants, from decorative flowers to root vegetables and leafy greens. While flavonoids are usually discussed in terms of fruit and vegetables, you’ll find them in cannabis, too. For example, purple kush — that purple tinge to each bud comes from the same sorts of flavonoids you’d
find in berries.

Taking terpenes and phytocannabinoids together is beneficial for:
● Pain
● Anxiety
● Inflammation
● Epilepsy
● Cancer
● Fungal Infection

When it comes to cannabis, we are most often concerned with how the two main cannabinoids, THC and CBD, work together.

1. Low THC + High CBD = little-to-no psychoactive effects.

2. High THC + Low CBD = psychoactive, but low amounts of CBD may dampen THC’s effects and increase the amount of time THC imparts its effects.

3. High THC + High CBD = psychoactive and sedative, with CBD increasing the amount of time THC spends in the body.

4. Low THC + Low CBD = perhaps an energizing effect, with the CBD potentially enhancing THC’s psychoactivity.

5. Equal ratio of THC + CBD = psychoactive, but less so than THC on its own. A potent anti-inflammatory.

CBD and THC can be taken in several ways, including:

● Capsules

● Gummies

● Food Products

● Tinctures

● Topicals

● Vapes


The entourage effect is a theory that illustrates the variety in compounds and phytochemicals present in the cannabis plant, and the different ways these can work together to improve well- being and provide great health benefits.
As more research is published, we hope this will lead to an incredible variety in CBD products and even more opportunities for positive effects on the body with whole plant cannabis.

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